Structure of PDB 3o1d Chain A

Receptor sequence
>3o1dA (length=240) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVS
YSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMS
WSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMA
ICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKL
ADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS
3D structure
PDB3o1d Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097.
ChainA
Resolution2.4007 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A I270 K274 I288 K292 P442 L443 E446 V447 E451 S453 I57 K61 I75 K79 P229 L230 E233 V234 E238 S240
BS02 G72 A L255 V262 S265 M300 R302 S303 S306 W314 C316 H333 L337 L341 H423 Y427 L430 L42 V49 S52 M87 R89 S90 S93 W101 C103 H120 L124 L128 H210 Y214 L217
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:3o1d, PDBe:3o1d, PDBj:3o1d
PDBsum3o1d
PubMed22180837
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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