Structure of PDB 3nys Chain A

Receptor sequence

>3nysA (length=359) Species: 208964 (Pseudomonas aeruginosa PAO1)

MIEFIDLKNQQARIKDKIDAGIQRVLRHGQYILGPEVTELEDRLADFVGA
KYCISCANGTDALQIVQMALGVGPGDEVITPGFTYVATAETVALLGAKPV
YVDIDPRTYNLDPQLLEAAITPRTKAIIPVSLYGQCADFDAINAIASKYG
IPVIEDAAQSFGASYKGKRSCNLSTVACTSFFPSAPLGCYGDGGAIFTND
DELATAIRQIARHGQDRRYHHIRVGVNSRLDTLQAAILLPKLEIFEEEIA
LRQKVAAEYDLSLKQVGIGTPFIEVNNISVYAQYTVRMDNRESVQASLKA
AGVPTAVHYPIPLNKQPAVADEKAKLPVGDKAATQVMSLPMHPYLDTASI
KIICAALTN

3D structure

• PDB: 3nys Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase.
• Chain: A
• Resolution: 1.45 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): Y85 D156 Q159 F182 A185 Y219 R229
• Catalytic site (residue number reindexed from 1): Y85 D156 Q159 F182 A185 Y219 R229
• Enzyme Commision number: 2.6.1.98: UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	PLP	A	N58 G59 T60 Y85 A87 D156 A158 Q159 S180	N58 G59 T60 Y85 A87 D156 A158 Q159 S180

Gene Ontology

Molecular Function

• GO:0008483 transaminase activity
• GO:0030170 pyridoxal phosphate binding

Biological Process

• GO:0000271 polysaccharide biosynthetic process
• GO:0006065 UDP-glucuronate biosynthetic process
• GO:0009103 lipopolysaccharide biosynthetic process
• GO:0009243 O antigen biosynthetic process
• GO:0071555 cell wall organization

External links

• PDB: RCSB:3nys, PDBe:3nys, PDBj:3nys
• PDBsum: 3nys
• PubMed: 28028852
• UniProt: Q9HZ76|WBPE_PSEAE UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase (Gene Name=wbpE)