Structure of PDB 3ny1 Chain A

Receptor sequence
>3ny1A (length=73) Species: 9606 (Homo sapiens) [Search protein sequence]
GSQLCGRVFKSGETTYSCRDCAIDPTCVLCMDCFQDSVHKNHRYKMHTST
GGGFCDCGDTEAWKTGPFCVNHE
3D structure
PDB3ny1 Structural basis of substrate recognition and specificity in the N-end rule pathway.
ChainA
Resolution2.085 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C99 C124 C127 C149 C5 C30 C33 C55
BS02 ZN A C127 C151 C163 H166 C33 C57 C69 H72
BS03 ZN A C112 C115 H133 H136 C18 C21 H39 H42
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:3ny1, PDBe:3ny1, PDBj:3ny1
PDBsum3ny1
PubMed20835242
UniProtQ8IWV7|UBR1_HUMAN E3 ubiquitin-protein ligase UBR1 (Gene Name=UBR1)

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