Structure of PDB 3nub Chain A

Receptor sequence
>3nubA (length=358) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
MIEFIDLKNQQARIKDKIDAGIQRVLRHGQYILGPEVTELEDRLADFVGA
KYCISCANGTDALQIVQMALGVGPGDEVITPGFTYVATAETVALLGAKPV
YVDIDPRTYNLDPQLLEAAITPRTKAIIPVSLYGQCADFDAINAIASKYG
IPVIEDAAQSFGASYKGKRSCNLSTVACTSFFPSKPLGCYGDGGAIFTND
DELATAIRQIARHGQDRRYHHIRVGVNSRLDTLQAAILLPKLEIFEEEIA
LRQKVAAEYDLSLKQVGIGTPFIEVNNISVYAQYTVRMDNRESVQASLKA
AGVPTAVHYPIPLNKQPAVADEKAKLPVGDKAATQVMSLPMHPYLDTASI
KIICAALT
3D structure
PDB3nub Structural Analysis of WbpE from Pseudomonas aeruginosa PAO1: A Nucleotide Sugar Aminotransferase Involved in O-Antigen Assembly
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y85 D156 Q159 F182 K185 Y219 R229
Catalytic site (residue number reindexed from 1) Y85 D156 Q159 F182 K185 Y219 R229
Enzyme Commision number 2.6.1.98: UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UD0 A I5 L7 N58 G59 T60 Y85 D156 A158 Q159 S180 F182 S184 K185 H308 Y309 I5 L7 N58 G59 T60 Y85 D156 A158 Q159 S180 F182 S184 K185 H308 Y309
BS02 UD0 A N227 R229 N227 R229
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0006065 UDP-glucuronate biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009243 O antigen biosynthetic process
GO:0071555 cell wall organization

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Molecular Function
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Biological Process
External links
PDB RCSB:3nub, PDBe:3nub, PDBj:3nub
PDBsum3nub
PubMed20604544
UniProtQ9HZ76|WBPE_PSEAE UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase (Gene Name=wbpE)

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