Structure of PDB 3ntr Chain A

Receptor sequence
>3ntrA (length=337) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MSLRIGVIGTGAIGKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQYQL
NATVYPNDDSLLADENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEVPLA
TTAEGCMRIVEEEIKVGKRLVQVGFMRRYDSGYVQLKEALDNHVIGEPLM
IHCAHRNPTVGDNYTTDMAVVDTLVHEIDVLHWLVNDDYESVQVIYPKKS
KNALPHLKDPQIVVIETKGGIVINAEIYVNCKYGYDIQCEIVGEDGIIKL
PEPSSISLRKEGRFSTDILMDWQRRFVAAYDVEIQDFIDSIQKKGEVSGP
TAWDGYIAAVTTDACVKAQESGQKEKVELKEKPEFYQ
3D structure
PDB3ntr Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification.
ChainA
Resolution2.6503 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) V97 H176
Catalytic site (residue number reindexed from 1) V97 H176
Enzyme Commision number 1.1.1.18: inositol 2-dehydrogenase.
1.1.1.369: D-chiro-inositol 1-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G11 A12 I13 D35 V36 S74 W75 A78 E96 V97 M126 W272 Y280 G11 A12 I13 D35 V36 S74 W75 A78 E96 V97 M126 W272 Y280
BS02 INS A T173 H176 T173 H176
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0050112 inositol 2-dehydrogenase (NAD+) activity
Biological Process
GO:0019310 inositol catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3ntr, PDBe:3ntr, PDBj:3ntr
PDBsum3ntr
PubMed20809899
UniProtP26935|IOLG_BACSU Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase (Gene Name=iolG)

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