Structure of PDB 3nq5 Chain A

Receptor sequence

>3nq5A (length=285) Species: 1404 (Priestia megaterium)

KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPG
SDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDP
SQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNF
GATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQL
HNRVHHWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPM
KNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDI

3D structure

• PDB: 3nq5 First structures of an active bacterial tyrosinase reveal copper plasticity.
• Chain: A
• Resolution: 2.3 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H60 H69
• Catalytic site (residue number reindexed from 1): H57 H66
• Enzyme Commision number: 1.14.18.1: tyrosinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CU	A	H42 H60	H39 H57
BS02	CU	A	H204 H208 H231	H201 H205 H228
BS03	ZN	A	H13 D287	H10 D284
BS04	ZN	A	H279 R280	H276 R277

Gene Ontology

Molecular Function

• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:3nq5, PDBe:3nq5, PDBj:3nq5
• PDBsum: 3nq5
• PubMed: 21040728
• UniProt: B2ZB02