Structure of PDB 3nmr Chain A

Receptor sequence
>3nmrA (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
SDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCC
FVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFI
GMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQ
TAIKAMHQAQTMEGCSSPMVVKFAD
3D structure
PDB3nmr Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A K109 F111 G113 M114 R138 L140 R148 G149 C150 F152 S178 S179 V182 K184 A186 D187 K97 F99 G101 M102 R126 L128 R136 G137 C138 F140 S166 S167 V170 K172 A174 D175 PDBbind-CN: Kd=0.65uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Cellular Component
GO:1990904 ribonucleoprotein complex

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Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:3nmr, PDBe:3nmr, PDBj:3nmr
PDBsum3nmr
PubMed20947024
UniProtQ92879|CELF1_HUMAN CUGBP Elav-like family member 1 (Gene Name=CELF1)

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