Structure of PDB 3nc6 Chain A

Receptor sequence
>3nc6A (length=374) Species: 1423 (Bacillus subtilis) [Search protein sequence]
IKLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFISRYHDVRYILQ
HPDIFTTKSLVERAAKRRIVVRSFIGDALDHLSPLIKQNAENLLAPYLER
GKSDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSGVADFITSISQSP
EARAHSLWCSEQLSQYLMPVIKERRVNPGSDLISILCTLSDKDILALILN
VLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRYKPP
VQLIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQPDVFNIHRE
DLGIKSAFSGAARHLAFGSGIHNCVGTAFAKNEIEIVANIVLDKMRNIRL
EEDFCYAESGLYTRGPVSLLVAFD
3D structure
PDB3nc6 Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
ChainA
Resolution3.1 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D163 A233 E236 P237 A238 C353 V354 G355 E362 T392
Catalytic site (residue number reindexed from 1) D141 A204 E207 P208 A209 C324 V325 G326 E333 T363
Enzyme Commision number 1.14.15.13: pulcherriminic acid synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A S63 L64 M143 N229 A233 A234 P237 V280 I283 R285 A345 F346 C353 V354 G355 F358 A359 S59 L60 M121 N200 A204 A205 P208 V251 I254 R256 A316 F317 C324 V325 G326 F329 A330
BS02 PIW A L64 E236 L60 E207
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0046148 pigment biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3nc6, PDBe:3nc6, PDBj:3nc6
PDBsum3nc6
PubMed20690619
UniProtO34926|CYPX_BACSU Pulcherriminic acid synthase (Gene Name=cypX)

[Back to BioLiP]