Structure of PDB 3nc5 Chain A

Receptor sequence
>3nc5A (length=384) Species: 1423 (Bacillus subtilis) [Search protein sequence]
KLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFISRYHDVRYILQH
PDIFTTKSLVERAEPVMRSAKRRIVVRSFIGDALDHLSPLIKQNAENLLA
PYLERGKSDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSGVADFITS
ISQSPEARAHSLWCSEQLSQYLMPVIKERRVNPGSDLISILCTSEYMALS
DKDILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRA
IAETLRYKPPVQLIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFE
QPDVFNIHREDLGIKSAFSGAARHLAFGSGIHNCVGTAFAKNEIEIVANI
VLDKMRNIRLEEDFCYAESGLYTRGPVSLLVAFD
3D structure
PDB3nc5 Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.
ChainA
Resolution2.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D163 A233 E236 P237 A238 C353 V354 G355 E362 T392
Catalytic site (residue number reindexed from 1) D146 A214 E217 P218 A219 C334 V335 G336 E343 T373
Enzyme Commision number 1.14.15.13: pulcherriminic acid synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A L64 N229 A233 A234 P237 R285 A345 F346 H351 C353 G355 F358 A359 L59 N210 A214 A215 P218 R266 A326 F327 H332 C334 G336 F339 A340
BS02 MG A D163 T166 D146 T149
BS03 MG A Q281 M307 I308 G309 Q262 M288 I289 G290
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0046148 pigment biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3nc5, PDBe:3nc5, PDBj:3nc5
PDBsum3nc5
PubMed20690619
UniProtO34926|CYPX_BACSU Pulcherriminic acid synthase (Gene Name=cypX)

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