Structure of PDB 3nbn Chain A

Receptor sequence
>3nbnA (length=423) Species: 9606 (Homo sapiens) [Search protein sequence]
PPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYL
MGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTA
KTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLK
NADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIHLL
DDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLD
ADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDG
ASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTG
QNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVP
VTLVRNDGIIYSTSLTFTYTPEP
3D structure
PDB3nbn Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes.
ChainA
Resolution3.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K50 R51 F52 K152 R178 K255 K271 K39 R40 F41 K141 R167 K244 K260
BS02 dna A Y46 S151 S154 K156 S159 K161 R180 Q182 Y35 S140 S143 K145 S148 K150 R169 Q171
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3nbn, PDBe:3nbn, PDBj:3nbn
PDBsum3nbn
PubMed20972443
UniProtQ06330|SUH_HUMAN Recombining binding protein suppressor of hairless (Gene Name=RBPJ)

[Back to BioLiP]