Structure of PDB 3n9v Chain A

Receptor sequence
>3n9vA (length=300) Species: 9606 (Homo sapiens) [Search protein sequence]
MIQNFRFFAGTYNVNGQSPKECLRLWLSNGIQAPDVYCVGFQELDLSKEA
FFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAY
ISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYER
RNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKV
KKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDD
WDTSRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVV
3D structure
PDB3n9v Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.36: phosphoinositide 5-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A N275 E303 N15 E43
BS02 CA A T371 G372 D414 T111 G112 D154
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity
GO:0052745 inositol phosphate phosphatase activity
Biological Process
GO:0046856 phosphatidylinositol dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3n9v, PDBe:3n9v, PDBj:3n9v
PDBsum3n9v
PubMed24704254
UniProtP32019|I5P2_HUMAN Type II inositol 1,4,5-trisphosphate 5-phosphatase (Gene Name=INPP5B)

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