Structure of PDB 3n9q Chain A

Receptor sequence

>3n9qA (length=484) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]

PKESDRCGGCGKFTHEDKKNDFQWIGCDSCQTWYHFLCSGLEQFEYYLYE
KFFCPKCVPHTGHSIRYKVVAPHRYRWYSPNEKHLGIEVGSKTWIEDFIT
RENTVPSPTDDEVCIVEDGYEFRREFEKLGGADNWGKVFMVKDMDGLNMT
MPKPGFDLEDVVKIMGSDYEVDTIDVYNQSTYSMKLDTFRKLFRDTKNRP
LLYNFLSLEFSDNNEMKEIAKPPRFVQEISMVNRLWPDVSGAEYIKLLQR
EEYLPEDQRPKVEQFCLAGMAGSYTDFHVDFGGSSVYYHILKGEKIFYIA
APTEQNFAAYQAHETSPDTTTWFGDIANGAVKRVVIKEGQTLLIPAGWIH
AVLTPVDSLVFGGNFLHLGNLEMQMRVYHLENAIRKEIRSEEKFYFPNFE
LLHWMYMRNVLLEKITEANQEGSDMREQEKNIWTASQIMKAEMERWMDRE
LRLGPEILPTDDKNKIMISVRKQIEIQTKIQNAK

3D structure

PDB

3n9q Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

Chain

Resolution

2.3 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.14.11.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	D196 F239 Q240 W241 I242 C244 D245 Q248 W250 Y266	D5 F22 Q23 W24 I25 C27 D28 Q31 W33 Y49
BS02	peptide	A	Q260 I391 Q396 S397 T398 S424 F482 E531 N581 E608 K610 F611	Q43 I174 Q179 S180 T181 S207 F265 E314 N364 E391 K393 F394
BS03	FE2	A	H495 D497 H567	H278 D280 H350
BS04	ZN	A	C198 C201 H252 C255	C7 C10 H35 C38
BS05	ZN	A	C244 C247 C271 C274	C27 C30 C54 C57

External links

PDB	RCSB:3n9q, PDBe:3n9q, PDBj:3n9q
PDBsum	3n9q
PubMed	20567261
UniProt	Q9GYI0\|KDM7_CAEEL Lysine-specific demethylase 7 homolog (Gene Name=jmjd-1.2)

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