Structure of PDB 3n9p Chain A

Receptor sequence

>3n9pA (length=487) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]

PKESDRCGGCGKFTHEDKKNDFQWIGCDSCQTWYHFLCSGLEQFEYYLYE
KFFCPKCVPHTGHSIRYKVVAPHRYRWYSPNEKHLGIEVGSKTWIEDFIT
RENTVPSPTDDEVCIVEDGYEFRREFEKLGGADNWGKVFMVKDMDGLNMT
MPKPGFDLEDVVKIMGSDYEVDTIDVYNQSTYSMKLDTFRKLFRDTKNRP
LLYNFLSLEFSDNNEMKEIAKPPRFVQEISMVNRLWPDVSGAEYIKLLQR
EEYLPEDQRPKVEQFCLAGMAGSYTDFHVDFGGSSVYYHILKGEKIFYIA
APTEQNFAAYQAHETSPDTTTWFGDIANGAVKRVVIKEGQTLLIPAGWIH
AVLTPVDSLVFGGNFLHLGNLEMQMRVYHLENAIRKEIRSEEKFYFPNFE
LLHWMYMRNVLLEKITEANQEGSDMREQEKNIWTASQIMKAEMERWMDRE
LRLGPEKNAILPTDDKNKIMISVRKQIEIQTKIQNAK

3D structure

PDB

3n9p Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

Chain

Resolution

2.388 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.14.11.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	D196 F239 Q240 W241 G243 C244 D245 Q248 W250 Y266	D5 F22 Q23 W24 G26 C27 D28 Q31 W33 Y49
BS02	peptide	A	Y292 D389 N395 Q396 S397 T398 S424 H495 D497 E531 N581 K610 F611 P614 N615	Y75 D172 N178 Q179 S180 T181 S207 H278 D280 E314 N364 K393 F394 P397 N398
BS03	FE2	A	H495 D497 H567	H278 D280 H350
BS04	ZN	A	C198 C201 H252 C255	C7 C10 H35 C38
BS05	ZN	A	C244 C247 C271 C274	C27 C30 C54 C57

External links

PDB	RCSB:3n9p, PDBe:3n9p, PDBj:3n9p
PDBsum	3n9p
PubMed	20567261
UniProt	Q9GYI0\|KDM7_CAEEL Lysine-specific demethylase 7 homolog (Gene Name=jmjd-1.2)

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