Structure of PDB 3n0s Chain A

Receptor sequence
>3n0sA (length=265) Species: 198094 (Bacillus anthracis str. Ames) [Search protein sequence]
NAMNDIVASTQLPNTIKTITNDLRKLGLKKGMTVIVHSSLSSIGWISGGA
VAVVEALMEVITEEGTIIMPTQSSDLSDPKHWSRPPVPEEWWQIIRDNVP
AFEPHITPTRAMGKVVECFRTYPNVVRSNHPLGSFAAWGRHAEEITVNQS
LSMSLGEESPLRKIYDLDGYILLIGVGYDSNTSVALSEVRSGACELIKVG
APIIENGERVWKEFVDMDYDSDKFVEIGVEFEQKGTVTMGKIGNAKCRLM
KQRDIVDFGTEWFRK
3D structure
PDB3n0s Structural Analysis of a Putative Aminoglycoside N-Acetyltransferase from Bacillus anthracis.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.81: aminoglycoside N(3)-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO A M1 I4 H35 S36 S37 L38 S39 I44 M110 G111 K112 V174 S178 T180 M3 I6 H37 S38 S39 L40 S41 I46 M112 G113 K114 V176 S180 T182 MOAD: Kd=3.72uM
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0046353 aminoglycoside 3-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:3n0s, PDBe:3n0s, PDBj:3n0s
PDBsum3n0s
PubMed21601576
UniProtA0A3P1UCA6

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