Structure of PDB 3mxy Chain A

Receptor sequence
>3mxyA (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKF
GNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDI
E
3D structure
PDB3mxy Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R67 R86 S96 H107 F108 K109 L120 W121 R16 R35 S45 H56 F57 K58 L69 W70
External links
PDB RCSB:3mxy, PDBe:3mxy, PDBj:3mxy
PDBsum3mxy
PubMed22001015
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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