Structure of PDB 3mte Chain A

Receptor sequence
>3mteA (length=219) Species: 562 (Escherichia coli) [Search protein sequence]
MLILKGTKTVDLSKDELTEIIGQFDRVHIDLGTGDGRNIYKLAINDQNTF
YIGIDPVKENLFDISKKIIKKPSKGGLSNVVFVIAAAESLPFELKNIADS
ISILFPWGTLLEYVIKPNRDILSNVADLAKKEAHFEFVTTYSDSYEEAEI
KKRGLPLLSKAYFLSEQYKAELSNSGFRIDDVKELDNEYVKQFNSLWAKR
LAFGRKRSFFRVSGHVSKH
3D structure
PDB3mte Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.
ChainA
Resolution1.805 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.180: 16S rRNA (adenine(1408)-N(1))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A G32 T33 G34 N38 D55 P56 A86 A87 E88 L104 F105 W107 W197 G32 T33 G34 N38 D55 P56 A86 A87 E88 L104 F105 W107 W197
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:3mte, PDBe:3mte, PDBj:3mte
PDBsum3mte
PubMed20639535
UniProtA8C927|NPMA_ECOLX 16S rRNA (adenine(1408)-N(1))-methyltransferase (Gene Name=npmA)

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