Structure of PDB 3mpz Chain A

Receptor sequence
>3mpzA (length=125) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
GSMVNWNALRSKAIEVSRHAYAPYSGFPVGAAALVDDGRTVTGCNVENVS
YGLGLCAECAVVCALHSGGGGRLVALSCVGPDGGVLMPCGRCRQVLLEHG
GPELLIDHAHGPRPLRELLPDAFGP
3D structure
PDB3mpz Increasing the structural coverage of tuberculosis drug targets.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.5: cytidine deaminase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C53 C86 C89 C56 C89 C92
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004126 cytidine deaminase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009972 cytidine deamination
GO:0055086 nucleobase-containing small molecule metabolic process
GO:0072527 pyrimidine-containing compound metabolic process
GO:1901135 carbohydrate derivative metabolic process
Cellular Component
GO:0005829 cytosol

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Biological Process

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Cellular Component
External links
PDB RCSB:3mpz, PDBe:3mpz, PDBj:3mpz
PDBsum3mpz
PubMed25613812
UniProtA0QT11

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