Structure of PDB 3mnq Chain A

Receptor sequence
>3mnqA (length=735) Species: 352472 (Dictyostelium discoideum AX4) [Search protein sequence]
EDPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECG
EIVSETSDSFTFKTVDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEP
AVFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNE
VAPHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVA
GRNQANGSGVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNSA
GFISGASIQSYLLEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAG
PESFNYLNQSGCVDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAG
ILHLGNIKFEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILA
GRDLVAQHLNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFI
GVLDISGFEIFKVNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEKIN
WTFIDFGLDSQATIDLIDGRQPPGILALLDEQSVFPNATDNTLITKLHSH
FSKKNAKYEEPRFSKTEFGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCF
KDSSDNVVTKLFNDPNIASRAKKGANFITVAAQYKEQLASLMATLETTNP
HFVRCIIPNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYAD
FVKRYRDAEDSQKATDADPEQYRFGITKIFFRAGQ
3D structure
PDB3mnq Structural basis of resveratrol regulation of myosin activity.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S181 G182 T186 N233 S236 S237 G457 E459
Enzyme Commision number 3.6.4.1: Transferred entry: 5.6.1.8.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AD9 A N127 P128 F129 S181 G182 G184 K185 T186 E187 N233 S236 S237 G457 N127 P128 F129 S181 G182 G184 K185 T186 E187 N233 S236 S237 G457
BS02 MG A T186 S237 T186 S237
BS03 STL A K229 T231 T274 K661 Q662 K229 T231 T274 K661 Q662
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:3mnq, PDBe:3mnq, PDBj:3mnq
PDBsum3mnq
PubMed
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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