Structure of PDB 3mno Chain A

Receptor sequence
>3mnoA (length=255) Species: 10090 (Mus musculus) [Search protein sequence]
MVPAALPQLTPTLVSLLEVIEPEVLYAGSVPDSAWRIMTTLNMLGGRQVI
AAVKWAKAIPGFRNLHLDDQMTLLQYSWMSLMVFALGWRSYRQASGNLLC
FAPDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLL
SSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLL
DSMHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKL
LFHQK
3D structure
PDB3mno Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K585 M599 Q603 E757 E761 N765 K57 M71 Q75 E229 E233 N237
BS02 DEX A M566 L569 N570 G573 Q576 M610 F629 Q648 M652 Y741 C742 T745 M38 L41 N42 G45 Q48 M82 F101 Q120 M124 Y213 C214 T217
External links
PDB RCSB:3mno, PDBe:3mno, PDBj:3mno
PDBsum3mno
PubMed20850457
UniProtP06537|GCR_MOUSE Glucocorticoid receptor (Gene Name=Nr3c1)

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