Structure of PDB 3mne Chain A

Receptor sequence
>3mneA (length=253) Species: 10090 (Mus musculus) [Search protein sequence]
MVPAALPQLTPTLVSLLEVIEPEVLYAGPDSAWRIMTTLNMLGGRQVIAA
VKWAKAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQASGNLLCFA
PDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLLSS
VPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDS
MHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKLLF
HQK
3D structure
PDB3mne Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.
ChainA
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V581 K585 M599 E761 V51 K55 M69 E231
BS02 DEX A M566 L569 N570 G573 Q576 M607 M610 F629 Q648 M652 Y741 C742 T745 M36 L39 N40 G43 Q46 M77 M80 F99 Q118 M122 Y211 C212 T215
External links
PDB RCSB:3mne, PDBe:3mne, PDBj:3mne
PDBsum3mne
PubMed20850457
UniProtP06537|GCR_MOUSE Glucocorticoid receptor (Gene Name=Nr3c1)

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