Structure of PDB 3mje Chain A

Receptor sequence
>3mjeA (length=470) Species: 40318 (Streptomyces nodosus) [Search protein sequence]
SHMDALRYHIEWNRVAEPGTARPAGRLLAVISPDHAGAPWVTAVLDALGP
DTVRFEAKGTDRAAWAAQLAQLREDEGEFHAVVSLLAAAEALHTDHGSVP
LGLAQTLLLAQALGDAGLTAPLWCLTRGGVAAGRGDVLSSPVQGALWGLG
RVIGLEHPDRWGGLIDLPETVDTRAAARLTGLLADAGGEDQLAIRGSGVL
ARRLAHAAPAVPGSGKRPPVHGSVLVTGGTGGIGGRVARRLAEQGAAHLV
LTSRRGADAPGAAELRAELEQLGVRVTIAACDAADREALAALLAELPEDA
PLTAVFHSAGVAHDDAPVADLTLGQLDALMRAKLTAARHLHELTADLDLD
AFVLFSSGAAVWGSGGQPGYAAANAYLDALAEHRRSLGLTASSVAWGTWG
EVGMHDRLVRQGVLAMEPEHALGALDQMLENDDTAAAITLMDWEMFAPAF
TANRPSALLSTVPEAVSALS
3D structure
PDB3mje Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
ChainA
Resolution1.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NDP A G225 G229 I230 S250 R251 R252 A280 S305 A306 G307 K330 S353 S354 Y367 W393 G394 T395 W396 G400 M401 G228 G232 I233 S253 R254 R255 A283 S308 A309 G310 K333 S356 S357 Y370 W396 G397 T398 W399 G403 M404
External links