Structure of PDB 3mha Chain A

Receptor sequence
>3mhaA (length=195) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
GPLPDAKPLVEEATAQTKALKSAHMVLTVNGKIPGLSLKTLSGDLTTNPT
AATGNVKLTLGGSDIDADFVVFDGILYATLTPNQWSDFGPAADIYDPAQV
LNPDTGLANVLANFADAKAEGRDTINGQNTIRISGKVSAQAVNQIAPPFN
ATQPVPATVWIQETGDHQLAQAQLDRGSGNSVQMTLSKWGEKVQV
3D structure
PDB3mha Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Z69 A M60 L62 G70 S72 L73 F104 F123 D128 Y130 P132 M25 L27 G35 S37 L38 F69 F88 D93 Y95 P97
Gene Ontology
Molecular Function
GO:0008289 lipid binding
GO:0035091 phosphatidylinositol binding
GO:0051861 glycolipid binding
Biological Process
GO:0006869 lipid transport
GO:0046677 response to antibiotic
Cellular Component
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall
GO:0009986 cell surface
GO:0097691 bacterial extracellular vesicle

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Molecular Function
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Cellular Component
External links
PDB RCSB:3mha, PDBe:3mha, PDBj:3mha
PDBsum3mha
PubMed20694006
UniProtP9WK45|LPRG_MYCTU Lipoarabinomannan carrier protein LprG (Gene Name=lprG)

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