Structure of PDB 3mad Chain A

Receptor sequence
>3madA (length=451) Species: 2734 (Symbiobacterium thermophilum) [Search protein sequence]
KPYRDRFPSHARLPRAGLPRAEILAEIAAMGAAESPAWRDGYASGAVYHG
DEHHIAFLNEVYALQSQSNPLHPDLWPSTAKFEAEVVAMTAHMLGGDAAG
GTVCGTVTSGGTESLLLAMKTYRDWARATKGITAPEAVVPVSAHAAFDKA
AQYFGIKLVRTPLDADYRADVAAMREAITPNTVVVAGSAPGYPHGVVDPI
PEIAALAAEHGIGCHVDACLGGFILPWAERLGYPVPPFDFRLEGVTSVSA
DTHKYGYGAKGTSVILYRRPDLLHYQYFIAADWPGGLYFSPTFAGSRPGA
LSATAWAAMLSLGEEGYLDATRRILQAADRLKAGVRAIPSLKILGDPLWV
IAVASDELNIYQVMEEMAGRGWRLNGLHRPPAFHVALTLRHTEPGVVDRF
LADLQDAVAQVRAHPEKATGMAPVYGMAAAAPPELVRQVLTGFIDLLYEV
H
3D structure
PDB3mad Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.2.27: sphinganine-1-phosphate aldolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 A A103 Y105 A46 Y48
Gene Ontology
Molecular Function
GO:0004058 aromatic-L-amino-acid decarboxylase activity
GO:0008117 sphinganine-1-phosphate aldolase activity
GO:0016829 lyase activity
GO:0016830 carbon-carbon lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
Biological Process
GO:0019752 carboxylic acid metabolic process
GO:0030149 sphingolipid catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3mad, PDBe:3mad, PDBj:3mad
PDBsum3mad
PubMed20696404
UniProtQ67PY4

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