Structure of PDB 3m94 Chain A

Receptor sequence
>3m94A (length=180) Species: 6253 (Ascaris suum) [Search protein sequence]
MRHPLQCHWALWYLKADRSKDWEDCLKQVAVFDTVEDFWSLYNHIQAASG
LTWGSDYYLFKEGIKPMWEDENNVKGGRWLVVVDKQKRAQLLDHYWLELL
MAIIGEQFEDNGEYICGAVVNVRQKGDKVSLWTRDSLKDDVNLRIGQILK
AKLEIPDTEPIRYEVHKTGSMVKPRIVIPS
3D structure
PDB3m94 Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H50 P51 Q53 V82 W86 N90 E145 M148 G152 E153 Q154 D157 H3 P4 Q6 V35 W39 N43 E98 M101 G105 E106 Q107 D110
BS02 M7M A W69 M114 W115 E116 N168 R170 K175 W22 M67 W68 E69 N121 R123 K128 PDBbind-CN: -logKd/Ki=5.08,Kd=8.4uM
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3m94, PDBe:3m94, PDBj:3m94
PDBsum3m94
PubMed21965542
UniProtQ6PKX2

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