Structure of PDB 3m93 Chain A

Receptor sequence
>3m93A (length=180) Species: 6253 (Ascaris suum) [Search protein sequence]
MRHPLQCHWALWYLKADRSKDWEDCLKQVAVFDTVEDFWSLYNHIQAASG
LTWGSDYYLFKEGIKPMWEDENNVKGGRWLVVVDKQKRAQLLDHYWLELL
MAIIGEQFEDNGEYICGAVVNVRQKGDKVSLWTRDSLKDDVNLRIGQILK
AKLEIPDTEPIRYEVHTGSMVKPRIVIPSK
3D structure
PDB3m93 Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H50 P51 Q53 V82 E83 W86 N90 E145 M148 G152 Q154 H3 P4 Q6 V35 E36 W39 N43 E98 M101 G105 Q107
BS02 M7G A W69 M114 W115 E116 R170 W22 M67 W68 E69 R123 PDBbind-CN: -logKd/Ki=6.62,Kd=0.24uM
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:3m93, PDBe:3m93, PDBj:3m93
PDBsum3m93
PubMed21965542
UniProtQ6PKX2

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