Structure of PDB 3m84 Chain A

Receptor sequence
>3m84A (length=348) Species: 177416 (Francisella tularensis subsp. tularensis SCHU S4) [Search protein sequence]
AMAGLKYEDAGVNIEAGNQAVERMKQHVKKTFTQDVLTGLGSFGSLYSLK
NIINNYDDPVLVQSIDGVGTKTKVAVMCGKFENLGYDLFSAATNDIVVMG
AKPITFLDYVAHDKLDPAIMEELVKGMSKACAECGVSLVGGETAEMPGVY
QAGEIDMVGVITGIVDRKRIINGENIKEGDIVFGLSSSGLHTNGYSFARK
LFFDVAGNKHTDTYPELEGKTIGDVLLEPHINYTNIIHDFLDNGVDIKGM
AHITGGGFIENIPRVLPQGLGAQIDKDSFATPAIFKLMQRIGDISEFEMY
RSFNMGIGMTIIASQDQFDKMQELAKKHTNTKLYQIGKITNSGKVEII
3D structure
PDB3m84 Crystal Structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis
ChainA
Resolution1.699 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.3.1: phosphoribosylformylglycinamidine cyclo-ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A S41 D107 G140 E141 S42 D108 G141 E142
Gene Ontology
Molecular Function
GO:0004637 phosphoribosylamine-glycine ligase activity
GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
GO:0046084 adenine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3m84, PDBe:3m84, PDBj:3m84
PDBsum3m84
PubMed
UniProtQ5NGF2

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