Structure of PDB 3m4a Chain A

Receptor sequence
>3m4aA (length=304) Species: 1299 (Deinococcus radiodurans) [Search protein sequence]
PSRTELLARRARIARLAVPPAYQDVYVSPDAENELQAFGRDAARLQYRYH
PDFVALKKWQRLTRFAGALPTLKVATTADLRASGLPPRKVMALMTRLLHV
ARFRVGSDIYARQHKTYGLSTLRQRHVVVDGNTVTFRFKGKHGVSQHKAT
SDRTLAANMQKLLDLPGPWLFQTVDAGGERRRIHSTELNAYLREVIGPFT
AKDFRTWGGTLLAAEYLAQQGTESSERQAKKVLVDCVKFVADDLGNTPAV
TRGSYICPVIFDRYLDGKVLDDYEPRTERQEAELEGLTRSEGALKRMLES
ERTL
3D structure
PDB3m4a Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.1: DNA topoisomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T110 L113 R114 S116 K122 R129 R186 T187 N191 T77 L80 R81 S83 K89 R96 R153 T154 N158
BS02 dna A P2 A111 R114 P1 A78 R81
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003916 DNA topoisomerase activity
GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity
Biological Process
GO:0006265 DNA topological change

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3m4a, PDBe:3m4a, PDBj:3m4a
PDBsum3m4a
PubMed20541510
UniProtQ9RWH8

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