Structure of PDB 3lx3 Chain A

Receptor sequence
>3lx3A (length=163) Species: 5855 (Plasmodium vivax) [Search protein sequence]
DQIAELLVESPLFSFNCAHFIAFKGFRETLHGHNYNVSLRLRGNIQGDGY
VIDFSILKEKVRKVCKQLDHHFILPMYSDVLNIQEVNDNFKITCEDNSEY
SFPKRDCVQIPIKHSSTEEIGLYILNQLIEEIDLPFLKTRSVNYMEVTVS
ESPSQKATVHRNI
3D structure
PDB3lx3 Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.3.12: 6-pyruvoyltetrahydropterin synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H28 H40 H42 E160 H19 H31 H33 E151
BS02 XTN A S125 T126 E127 S116 T117 E118
Gene Ontology
Molecular Function
GO:0003874 6-pyruvoyltetrahydropterin synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006729 tetrahydrobiopterin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3lx3, PDBe:3lx3, PDBj:3lx3
PDBsum3lx3
PubMed
UniProtA5K2B2

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