Structure of PDB 3lw6 Chain A

Receptor sequence
>3lw6A (length=241) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
GASVHKMALLVPFRDRFEELLQFVPHMTAFLKRQGVAHHIFVLNQVDRFR
FNRASLINVGFQFASDVYDYIAMHDVDLLPLNDNLLYEYPSSLGPLHIAG
PKLHPKYHYDNFVGGILLVRREHFKQMNGMSNQYWGWGLEDDEFFVRIRD
AGLQVTRPQNIKTGTNDTFSHIHNRYHRKRDTQKCFNQKEMTRKRDHKTG
LDNVKYKILKVHEMLIDQVPVTILNILLDCDVNKTPWCDCS
3D structure
PDB3lw6 Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7.
ChainA
Resolution1.81 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D145 D147 W207 E210 D211 T238 H241 H243
Catalytic site (residue number reindexed from 1) D75 D77 W137 E140 D141 T168 H171 H173
Enzyme Commision number 2.4.1.133: xylosylprotein 4-beta-galactosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UDP A P82 F83 R84 R86 F121 D145 V146 D147 Y177 H241 H243 R250 P12 F13 R14 R16 F51 D75 V76 D77 Y107 H171 H173 R180
BS02 MN A D147 H241 H243 D77 H171 H173
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3lw6, PDBe:3lw6, PDBj:3lw6
PDBsum3lw6
PubMed20236943
UniProtQ9VBZ9|B4GT7_DROME Beta-1,4-galactosyltransferase 7 (Gene Name=beta4GalT7)

[Back to BioLiP]