Structure of PDB 3lrn Chain A

Receptor sequence
>3lrnA (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
KENKKLLCRKCKALACYTADVRVIEESHYTVLGDAFKECFVSRPHPKPKQ
FSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGVQ
TLYSKWKDFHFEKIPFDPAEM
3D structure
PDB3lrn The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A S829 H830 H847 F853 K858 K861 I875 K888 W908 S27 H28 H45 F51 K56 K59 I73 K86 W106 PDBbind-CN: Kd=0.32nM
BS02 ZN A C810 C813 C864 C869 C8 C11 C62 C67
External links
PDB RCSB:3lrn, PDBe:3lrn, PDBj:3lrn
PDBsum3lrn
PubMed20637642
UniProtO95786|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)

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