Structure of PDB 3lre Chain A

Receptor sequence
>3lreA (length=289) Species: 9606 (Homo sapiens) [Search protein sequence]
MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDNKDLKFVFDAVFDETS
TQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVMY
LTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVREDTQ
KGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHATSSRSHAVFQIYLRQQ
DKTASINQNVRIAKMSLIDLAGSERNRSLLALGNVINALAIPYRNSKLTR
LLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAK
3D structure
PDB3lre Insight into the molecular mechanism of the multitasking kinesin-8 motor.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R19 P20 G116 G118 K119 T120 H121 R8 P9 G82 G84 K85 T86 H87
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:3lre, PDBe:3lre, PDBj:3lre
PDBsum3lre
PubMed20818331
UniProtQ8NI77|KI18A_HUMAN Kinesin-like protein KIF18A (Gene Name=KIF18A)

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