Structure of PDB 3loo Chain A

Receptor sequence

>3looA (length=335) Species: 7165 (Anopheles gambiae)

LRDGMLVGLGNPLLDISAVVEKDLLNKYDMQPNNAILAEEKHMPMYQELI
EKYQAEYIAGGSVQNSLRVAQWILQRPRTAIFFGCVGQDEYARILEERAT
SNGVNVQYQRSATSPTGTCAVLVTGTQRSLCANLAAANDFTPEHLRSDGN
RAYLQGAQFFYVSGFFFTVSFESALSVAKEAAATGRMFMMNLSAPFVPQF
YKNNLEEIFPYVDVLFGNETEAIALAKEFNYGTEDLREIGKRIAALPKEN
GKRKRIVIITQGSDPVLLIEAGTDNVREFPVQKLATNGAGDAFVGGFLAQ
LLQSRTVDVCIKCGIWAAREIIQRSGCTFEGEPSF

3D structure

• PDB: 3loo A High-Affinity Adenosine Kinase from Anopheles gambiae.
• Chain: A
• Resolution: 2.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	B4P	A	N14 L16 D18 G64 C122 A135 F168 T263 G265 S266 V284 L287 N296 G297 A298 G299 D300 A327 I331	N11 L13 D15 G61 C119 A132 F165 T260 G262 S263 V281 L284 N287 G288 A289 G290 D291 A318 I322	MOAD: Ki=860nM PDBbind-CN: -logKd/Ki=6.07,Ki=860nM

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 16 02:47:12 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '3loo', asym_id = 'A', title = 'A High-Affinity Adenosine Kinase from Anopheles gambiae.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='3loo', asym_id='A', title='A High-Affinity Adenosine Kinase from Anopheles gambiae.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0004001,0006166,0016301', uniprot = '', pdbid = '3loo', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0004001,0006166,0016301', uniprot='', pdbid='3loo', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>