Structure of PDB 3lcp Chain A

Receptor sequence
>3lcpA (length=234) Species: 9606 (Homo sapiens) [Search protein sequence]
LPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSSDQIRVAPSLKSQR
GSVWTKTKAAFENWEVEVTFRVTGRGRIGADGLAIWYAENQGLEGPVFGS
ADLWNGVGIFFDSFDNDGKKNNPAIVIIGNNGQIHYDHQNDGASQALASC
QRDFRNKPYPVRAKITYYQNTLTVMINNGFTPDKNDYEFCAKVENMIIPA
QGHFGISAATGGLADDHDVLSFLTFQLTEPGKEP
3D structure
PDB3lcp Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D152 F154 N156 D181 D112 F114 N116 D141
BS02 CA A D155 D157 N161 N162 D181 D115 D117 N121 N122 D141
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3lcp, PDBe:3lcp, PDBj:3lcp
PDBsum3lcp
PubMed20138881
UniProtP49257|LMAN1_HUMAN Protein ERGIC-53 (Gene Name=LMAN1)

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