Structure of PDB 3lcm Chain A

Receptor sequence
>3lcmA (length=196) Species: 210007 (Streptococcus mutans UA159) [Search protein sequence]
MKILIVYTHPNPTSFNAEILKQVQTNLSKEHTVSTLDLYAEHFDPVLQFN
ETHKRRDLAKVAEMEKYRDLVTWADHLIFIFPIWWSGMPAILKGFIDRVF
VADFAYSYKKVGLEGHLQGKSAWIITTHNTPSFAMPFVQDYGKVLKKQIL
KPCAISPVKLTELTSIEKISDDERQKLLHKVAQITRNILEHHHHHH
3D structure
PDB3lcm Structural and biochemical characterization of MdaB from cariogenic Streptococcus mutans reveals an NADPH-specific quinone oxidoreductase
ChainA
Resolution1.799 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N129 M135 Y141
Catalytic site (residue number reindexed from 1) N129 M135 Y141
Enzyme Commision number 1.6.5.2: NAD(P)H dehydrogenase (quinone).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A H9 S14 F15 N16 P82 I83 W84 W85 S86 T127 H128 N129 T130 Y141 R174 H9 S14 F15 N16 P82 I83 W84 W85 S86 T127 H128 N129 T130 Y141 R174
BS02 NAP A Y106 Y108 Y106 Y108
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003955 NAD(P)H dehydrogenase (quinone) activity
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:3lcm, PDBe:3lcm, PDBj:3lcm
PDBsum3lcm
PubMed24699637
UniProtQ8DTD1

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