Structure of PDB 3l81 Chain A

Receptor sequence
>3l81A (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
NEVFLDVVERLSVLIASNGSLLKVDVQGEIRLKSFLPSGSEMRIGLTEEF
SVGKSELRGYGPGIRVDEVSFHSSVNLDEFESHRILRLQPPQGELTVMRY
QLSDDLPSPLPFRLFPSVQWDRGSGRLQVYLKLRCDLLSKSQALNVRLHL
PLPRGVVSLSQELSSPEQKAELAEGALRWDLPRVQGGSQLSGLFQMDVPG
PPGLGLGPASLSFELPRHTCSGLQVRFLRLAFPHKWVRHLSHSDAYVIRI
3D structure
PDB3l81 Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S254 F255 H256 S257 L261 F264 T280 R283 S70 F71 H72 S73 L77 F80 T96 R99
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:3l81, PDBe:3l81, PDBj:3l81
PDBsum3l81
PubMed20230749
UniProtO00189|AP4M1_HUMAN AP-4 complex subunit mu-1 (Gene Name=AP4M1)

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