Structure of PDB 3l3z Chain A

Receptor sequence
>3l3zA (length=249) Species: 9606 (Homo sapiens) [Search protein sequence]
SQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW
AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDL
VFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPV
DGLKNQKFFDELRMNYIKELDRIIACKKNPTSCSRRFYQLTKLLDSVQPI
ARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB3l3z Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V716 K720 V730 M734 Q738 E893 M894 V48 K52 V62 M66 Q70 E224 M225
BS02 DHT A L701 L704 N705 Q711 M749 F764 T877 L33 L36 N37 Q43 M81 F96 T208 BindingDB: IC50=>10000nM,EC50=6nM,Ki=0.2nM
External links
PDB RCSB:3l3z, PDBe:3l3z, PDBj:3l3z
PDBsum3l3z
PubMed20086010
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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