Structure of PDB 3l3x Chain A

Receptor sequence
>3l3xA (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
SQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW
AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDL
VFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPV
DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQP
IARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB3l3x Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V716 K720 R726 M734 Q738 M894 V48 K52 R58 M66 Q70 M226
BS02 DHT A L701 L704 N705 Q711 M745 M749 F764 T877 M895 L33 L36 N37 Q43 M77 M81 F96 T209 M227 BindingDB: IC50=>10000nM,EC50=6nM,Ki=0.2nM
External links
PDB RCSB:3l3x, PDBe:3l3x, PDBj:3l3x
PDBsum3l3x
PubMed20086010
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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