Structure of PDB 3kz7 Chain A

Receptor sequence
>3kz7A (length=119) Species: 10090 (Mus musculus) [Search protein sequence]
EGPPKYTKSILKKGDKTNFPKKGDVVHCWYTGTLPDGTVFDTNIQTSSKK
KKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPD
AKIPPNTKLIFEVELVDID
3D structure
PDB3kz7 Diversified targets of FKBP25 and its complex with rapamycin.
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y135 F145 D146 I172 Y198 F216
Catalytic site (residue number reindexed from 1) Y30 F40 D41 I67 Y93 F111
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RAP A D146 L162 G169 K170 V171 I172 W175 Y198 D41 L57 G64 K65 V66 I67 W70 Y93
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:3kz7, PDBe:3kz7, PDBj:3kz7
PDBsum3kz7
PubMed24879919
UniProtQ62446|FKBP3_MOUSE Peptidyl-prolyl cis-trans isomerase FKBP3 (Gene Name=Fkbp3)

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