Structure of PDB 3ku0 Chain A

Receptor sequence
>3ku0A (length=251) Species: 3979 (Suregada multiflora) [Search protein sequence]
GLDTVSFSTKGATYITYVNFLNELRVKLKPEGNSHGIPLLRKKCDDPGKC
FVLVALSNDNGQLAEIAIDVTSVYVVGYQVRNRSYFFKDAPDAAYEGLFK
NTIKTRLHFGGSYPSLEGEKAYRETTDLGIEPLRIGIKKLDENAIDNYKP
TEIASSLLVVIQMVSEAARFTFIENQIRNNFQQRIRPANNTISLENKWGK
LSFQIRTSGANGMFSEAVELERANGKKYYVTAVDQVKPKIALLKFVDKDP
K
3D structure
PDB3ku0 A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) V75 E166 R169
Catalytic site (residue number reindexed from 1) V75 E166 R169
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A Y74 V75 G111 Y113 I161 S165 R169 Y74 V75 G111 Y113 I161 S165 R169
Gene Ontology
Molecular Function
GO:0030598 rRNA N-glycosylase activity
Biological Process
GO:0017148 negative regulation of translation

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Molecular Function
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Biological Process
External links
PDB RCSB:3ku0, PDBe:3ku0, PDBj:3ku0
PDBsum3ku0
PubMed19913503
UniProtP33186|RIPG_SURMU Ribosome-inactivating protein gelonin (Gene Name=GEL)

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