Structure of PDB 3kpl Chain A

Receptor sequence

>3kplA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFYTAMSRPGRGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAP
WIEQEGPEYWDRETQISKTNTQTYRENLRTALRYYNQSEAGSHIIQRMYG
CDVGPDGRLLRGYDQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDHEVT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP

3D structure

PDB

3kpl T cell allorecognition via molecular mimicry.

Chain

Resolution

1.96 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 Y9 K45 Y59 E63 I66 T69 E76 N77 Y84 I95 Y99 D116 Y123 T143 K146 W147 V152 Q155 D156 Y159 L163 S167 R170 Y171	Y7 Y9 K45 Y59 E63 I66 T69 E76 N77 Y84 I95 Y99 D116 Y123 T143 K146 W147 V152 Q155 D156 Y159 L163 S167 R170 Y171

External links

PDB	RCSB:3kpl, PDBe:3kpl, PDBj:3kpl
PDBsum	3kpl
PubMed	20064448
UniProt	P01889\|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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