Structure of PDB 3kmd Chain A

Receptor sequence
>3kmdA (length=200) Species: 9606 (Homo sapiens) [Search protein sequence]
PLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTC
PVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPP
QHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSS
CMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRK
3D structure
PDB3kmd Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S241 R248 R273 C275 R280 S150 R157 R182 C184 R189
BS02 dna A K120 R248 K29 R157
BS03 ZN A C176 H179 C238 C242 C85 H88 C147 C151
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3kmd, PDBe:3kmd, PDBj:3kmd
PDBsum3kmd
PubMed20159469
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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