Structure of PDB 3kll Chain A

Receptor sequence

>3kllA (length=1007) Species: 1598 (Limosilactobacillus reuteri)

QYYIDPTTGQPRKNFLLQNGNDWIYFDKDTGAGTNALKLQFDKGTISADE
QYRRGNEAYSYDDKSIENVNGYLTADTWYRPKQILKDGTTWTDSKETDMR
PILMVWWPNTVTQAYYLNYMKQYGNLLPASLPSFSTDADSAELNHYSELV
QQNIEKRISETGSTDWLRTLMHEFVTKNSMWNKDSENVDYGGLQLQGGFL
KYVNSDLTKYANSDWRLMNRTATNIDGKNYGGAEFLLANDIDNSNPVVQA
EELNWLYYLMNFGTITGNNPEANFDGIRVDAVDNVDVDLLSIARDYFNAA
YNMEQSDASANKHINILEDWGWDDPAYVNKIGNPQLTMDDRLRNAIMDTL
SGAPDKNQALNKLITQSLVNRANDNTENAVIPSYNFVRAHDSNAQDQIRQ
AIQAATGKPYGEFNLDDEKKGMEAYINDQNSTNKKWNLYNMPSAYTILLT
NKDSVPRVYYGDLYQDGGQYMEHKTRYFDTITNLLKTRVKYVAGGQTMSV
DKNGILTNVRFGKGAMNATDTGTDETRTEGIGVVISNNTNLKLNDGESVV
LHMGAAHKNQKYRAVILTTEDGVKNYTNDTDAPVAYTDANGDLHFTNTNL
DGQQYTAVRGYANPDVTGYLAVWVPAGAADDQDARTAPSDEAHTTKTAYR
SNAALDSNVIYEGFSNFIYWPTTESERTNVRIAQNADLFKSWGITTFELA
PQYNSSKDGTFLDSIIDNGYAFTDRYDLGMSTPNKYGSDEDLRNALQALH
KAGLQAIADWVPDQIYNLPGKEAVTVTRSDDHGTTWEVSPIKNVVYITNT
IGGGEYQKKYGGEFLDTLQKEYPQLFSQVYPVTQTTIDPSVKIKEWSAKY
FNGTNILHRGAGYVLRSNDGKYYNLGTSTQQFLPSQLSVQDNEGYGFVKE
GNNYHYYDENKQMVKDAFIQDSVGNWYYLDKNGNMVANQSPVEISSNGAS
GTYLFLNNGTSFRSGLVKTDAGTYYYDGDGRMVRNQTVSDGAMTYVLDEN
GKLVSES

3D structure

• PDB: 3kll Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes
• Chain: A
• Resolution: 2.0 Å

Enzymatic activity

• Enzyme Commision number: 2.4.1.5: dextransucrase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	A	W1065 D1136	W320 D391
BS02	GLC	A	N1029 E1063 W1065	N284 E318 W320
BS03	GLC	A	D1028 W1065 G1066	D283 W320 G321
BS04	GLC	A	Y975 H1527	Y230 H782
BS05	GLC	A	T1530 W1531 E1532 V1533	T785 W786 E787 V788
BS06	GLC	A	R1086 Q1111 S1112	R341 Q366 S367
BS07	GLC	A	T1110 S1112 L1113 N1115	T365 S367 L368 N370
BS08	CA	A	E979 D985 N1029 D1508	E234 D240 N284 D763

Gene Ontology

Molecular Function

• GO:0046527 glucosyltransferase activity

Biological Process

• GO:0009250 glucan biosynthetic process

External links

• PDB: RCSB:3kll, PDBe:3kll, PDBj:3kll
• PDBsum: 3kll
• PubMed: 21118988
• UniProt: Q5SBN3