Structure of PDB 3kl8 Chain A

Receptor sequence
>3kl8A (length=256) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
DNYDVKEEVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQ
HPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQ
ILESIAYCHSNGIVHRNLKPENLLLASKAKGAAVKLADFGLAIEVNDSEA
WHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQH
RLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVP
WICNRE
3D structure
PDB3kl8 Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
ChainA
Resolution3.372 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) N135 K137 E139 N140 D156 T175
Catalytic site (residue number reindexed from 1) N117 K119 E121 N122 D138 T157
Enzyme Commision number 2.7.11.17: calcium/calmodulin-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q68 P70 Q50 P52
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3kl8, PDBe:3kl8, PDBj:3kl8
PDBsum3kl8
PubMed20139983
UniProtO62305|KCC2D_CAEEL Calcium/calmodulin-dependent protein kinase type II (Gene Name=unc-43)

[Back to BioLiP]