Structure of PDB 3kko Chain A

Receptor sequence
>3kkoA (length=169) Species: 10090 (Mus musculus) [Search protein sequence]
NLPTYKLVVVGDGGVGKSALTIQFFQKIFVDEYDPTIEDSYRKHTEIDNQ
WAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQL
ILRVKDRESFPMILVANKVDLMHLRKVTRDQGKEMATKYNIPYIETSAKD
PPLNVDKTFHDLVRVIRQQ
3D structure
PDB3kko Structural basis for conformational dynamics of GTP-bound Ras protein
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A G23 G25 K26 S27 A28 F38 V39 D40 Y42 P44 T45 G70 N126 K127 D129 L130 S156 G14 G16 K17 S18 A19 F29 V30 D31 Y33 P35 T36 G61 N117 K118 D120 L121 S147
BS02 MG A S27 T45 S18 T36
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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External links
PDB RCSB:3kko, PDBe:3kko, PDBj:3kko
PDBsum3kko
PubMed20479006
UniProtO08989|RASM_MOUSE Ras-related protein M-Ras (Gene Name=Mras)

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