Structure of PDB 3kkn Chain A

Receptor sequence
>3kknA (length=166) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPSIEDSYRKQVVIDGET
CLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQI
KRVKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQ
GVEDAFYTLVREIRQH
3D structure
PDB3kkn Structural basis for conformational dynamics of GTP-bound Ras protein
ChainA
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A G13 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147 G13 G15 K16 S17 A18 N116 K117 D119 L120 S145 A146 K147
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3kkn, PDBe:3kkn, PDBj:3kkn
PDBsum3kkn
PubMed20479006
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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