Structure of PDB 3kkm Chain A

Receptor sequence
>3kkmA (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPSIEDSYRKQVVIDGET
CLLDILDTAGMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPM
VLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVR
EIRQH
3D structure
PDB3kkm Structural basis for conformational dynamics of GTP-bound Ras protein
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A G13 G15 K16 S17 A18 F28 D30 Y32 G60 N116 K117 D119 L120 S145 A146 G13 G15 K16 S17 A18 F28 D30 Y32 G60 N105 K106 D108 L109 S134 A135
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3kkm, PDBe:3kkm, PDBj:3kkm
PDBsum3kkm
PubMed20479006
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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