Structure of PDB 3kj0 Chain A

Receptor sequence
>3kj0A (length=157) Species: 9606 (Homo sapiens) [Search protein sequence]
GSDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDG
VQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLIS
FGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF
HVEDLEG
3D structure
PDB3kj0 Mcl-1-Bim complexes accommodate surprising point mutations via minor structural changes.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A V220 H224 M231 L235 R248 V249 H252 V253 D256 N260 G262 R263 T266 F318 F319 V51 H55 M62 L66 R79 V80 H83 V84 D87 N91 G93 R94 T97 F149 F150
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:3kj0, PDBe:3kj0, PDBj:3kj0
PDBsum3kj0
PubMed20066663
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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