Structure of PDB 3ki4 Chain A

Receptor sequence
>3ki4A (length=199) Species: 666 (Vibrio cholerae) [Search protein sequence]
HMAVITPQGVTNWTYQELEATHQALTREGYVFVGYHGTNHVAAQTIVNRI
APVTENEEKWGGLYVATHAEVAHGYARIKEGTGEYGLPTRAERDARGVML
RVYIPRASLERFYRTNTPLENAEEHITQVIGHSLPLRNEAFTGPESAGGE
DETVIGWDMAIHAVAIPSTIPGNAYEELAIDEEAVAKEQSISTKPPYKE
3D structure
PDB3ki4 Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) E581
Catalytic site (residue number reindexed from 1) E152
Enzyme Commision number 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G9P A H460 G461 Y493 V494 A501 Y504 E581 H36 G37 Y64 V65 A72 Y75 E152
Gene Ontology
Molecular Function
GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:3ki4, PDBe:3ki4, PDBj:3ki4
PDBsum3ki4
PubMed
UniProtQ5EK40|CHXA_VIBCL Cholix toxin (Gene Name=chxA)

[Back to BioLiP]