Structure of PDB 3ki2 Chain A

Receptor sequence
>3ki2A (length=198) Species: 666 (Vibrio cholerae) [Search protein sequence]
GSHMAVITPQGVTNWTYQELEATHQALTREGYVFVGYHGTNHVAAQTIVN
RIAPNEEKWGGLYVATHAEVAHGYARIKEGTGEYGLPTRAERDARGVMLR
VYIPRASLERFYRTNTPLENAEEHITQVIGHSLPLRNEAFTGPESAGGED
ETVIGWDMAIHAVAIPSTIPGNAYEELAIDEEAVAKEQSISTKPPYKE
3D structure
PDB3ki2 Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
ChainA
Resolution1.28 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E581
Catalytic site (residue number reindexed from 1) E151
Enzyme Commision number 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G9G A H460 G461 Y493 A501 Y504 H38 G39 Y63 A71 Y74
BS02 G9G A L449 E452 Y454 V593 L27 E30 Y32 V163
Gene Ontology
Molecular Function
GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:3ki2, PDBe:3ki2, PDBj:3ki2
PDBsum3ki2
PubMed
UniProtQ5EK40|CHXA_VIBCL Cholix toxin (Gene Name=chxA)

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