Structure of PDB 3ki1 Chain A

Receptor sequence
>3ki1A (length=196) Species: 666 (Vibrio cholerae) [Search protein sequence]
GSHMAVITPQGVTNWTYQELEATHQALTREGYVFVGYHGTNHVAAQTIVN
RIAPEKWGGLYVATHAEVAHGYARIKEGTGEYGLPTRAERDARGVMLRVY
IPRASLERFYRTNTPLENAEEHITQVIGHSLPLRNEAFTGPESAGGEDET
VIGWDMAIHAVAIPSTIPGNAYEELAIDEEAVAKEQSISTKPPYKE
3D structure
PDB3ki1 Structure function analysis of soluble inhibitors of cholix toxin from Vibrio cholerae
ChainA
Resolution1.43 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E581
Catalytic site (residue number reindexed from 1) E149
Enzyme Commision number 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G9F A H460 G461 Y493 A501 Y504 E581 H38 G39 Y61 A69 Y72 E149
BS02 G9F A T445 A448 L449 E452 Y454 V593 T23 A26 L27 E30 Y32 V161
Gene Ontology
Molecular Function
GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:3ki1, PDBe:3ki1, PDBj:3ki1
PDBsum3ki1
PubMed
UniProtQ5EK40|CHXA_VIBCL Cholix toxin (Gene Name=chxA)

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